So far, I've tolerated Avastin twice a month and weekly Taxol quite well. I had dry mouth & chronic sore throat from Avastin, but Biotin helped. Now, yesterday and today - a new pain - mild chest pain. I'm not too concerned - I've had angina worse than this. I've put a call into the oncology nurse to let them know. If it becomes more serious, I will go to the ER, but I do NOT want to spend 12 hours waiting in ER over a mild chest pain. One of the side effects of Avastin is weakening of the heart, possible blood clots, heart attacks etc so I'm not 100% comfortable with this new symptom. I'm just wondering if anyone else experienced this and what it turned out to be.