P.S. I too find it frustrating to hear that Health Canada tends to be 'behind' when it comes to approval and support of new treatment options. Let's hope with OCC's help and our voices, that we can continue to change that!
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Original Message:
Sent: 08-18-2025 07:26
From: GloHo
Subject: Paclitaxel and Gemcitabine Combination
@DeniseBR
It looks like we are at about the same point in our journeys. Sending hugs 🥰.
@Alwayslearning
I'm just going to do a quick weigh in here. Over the course of my research throughout the years, I have seen research reports supporting many different doublet treatments with standard of care drugs, including GEM + PAC. Unfortunately, the drug formulary for OC standard of care treatments either does not include these regimens or they are restricted to certain points in your care. You can sometimes find trials that are exploring different combinations but standard of care treatment options have not been changed/updated by Health Canada.
My next standard of care option is Gemcitibine and the Gem+Pac combo is actually a treatment option that I will be asking about again!! You never know, there may be a work-around 😁 .
With two standard of care drugs like Gem+Pac, and the positive research results I've seen supporting this doublet, you would think that this option would be available already. Maybe they need more data? Who knows. It just takes so long for new treatment options to become available in Canada.
If you're wondering about the drug formulary…it's a list of single and regimens of drugs approved in Canada for use with specific cancers. The drug monograph provides the specific use for each drug or combo (second line, resistant, no more than x prior treatments, etc.)…very restricting and disheartening.
I use the Cancer Care drug formulary…I just find it easier to navigate.
Drug Formulary
Cancercareontario | remove preview |
| Drug Formulary | Drug Formulary information is intended for use by healthcare professionals. It is not intended to be medical advice. Some of the information, including information about funding for cancer drugs, does not apply to all patients. Cancer treatment plans are unique to each patient. | View this on Cancercareontario > |
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If you are going to take a peek, use the filter option to get the list for OC drugs, then you can look at single or regimens. If you click on the drug monograph, most spell out at which stage of a journey the drugs can be used.
I have used this resource often. I got tired of the Drs always saying "no" (usually with the qualifier that it's not funded$ for me at this stage of my journey) and wanted to see what they were basing their responses/decisions on 😁.
If anyone has any questions…let me know.
Original Message:
Sent: 08-17-2025 14:41
From: Melinda Gasson
Subject: Paclitaxel and Gemcitabine Combination
@DeniseBR out of curiosity who mentioned the combination treatment option? I'm always curious if the information is coming from patients vs. medical providers. Thanks.
Original Message:
Sent: 02-05-2025 09:05
From: DeniseBR
Subject: Paclitaxel and Gemcitabine Combination
Hi,
I received two series of Carboplatin & Paclitaxel from 2023-24. With quick recurrence after the second series, I was changed to a combination of Avastin and Caelyx, but that's stopped working after a few months.
Now I have started weekly Paclitaxel only treatment. But it's been recently mentioned to me that combining Gemcitabine with Paclitaxel might be a more effective option, but that wasn't offered to me. Does anyone have any experience with this combination?
Thank you ..