I have been taking Niraparib for three years after having a first recurrence, succesfully treated with carboplatin. I do not have a BRCA mutation. My only notable side effect is constipation, but I have a wonderful naturopath who has helped me manage it. My oncologist is concerned about the lack of data for women in my situation, which means there is no clear "data-driven" guidance for him to give. Some women get a secondary cancer (leukemia) when on Niraparib for an extended time, so that is the risk of continuing its use. They have no way to know if I am "cured" or if the Niraparib is keeping the cancer under control. There is also no way to know if it will continue to work for me. Together, we decideed that I would continue to use it, but at a reduced dose. My oncologist will continue to chat with me every 3 months. Is anyone else in a similar situation? If so, I wonder what your oncologist has suggested.
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