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Anyone here participating or thinking about participating in the Gloriosa Clinical Trial? https://clinicaltrials.gov/study/NCT05445778

@jobo

Hmmm…the fact that the trial is in phase 3 indicates that it may be a promising trial.

The drug is Elahere with Beva for platinum-sensitive participants with FRa expression.

Elahere is currently in approval process for platinum-resistant use.

This sounds like something I would definitely discuss with my Onc if I were eligible. I haven't done extensive research on Elahere for platinum-sensitive…but, the fact that it is in Phase 3 sounds like they may be having some success with this combo and it is being conducted in many locations.

Hi @Gloho. Yes, it was my gyne onc in Ottawa who had suggested it to me. She's the lead for this location and we started the pre-screening process, when she suddenly got a notice saying that the clinical trial is closed. I hadn't decided yet whether I really wanted to participate, but she suggested there was no harm in doing the pre-screening, which involved sending my tumor somewhere in the states to determine if it was folate alpha receptive or not. She's hoping that they will still go ahead and send us the results for my tumor, since they sent it in more than 2 weeks ago, but we are still waiting to hear.

@jobo

Hmmm…do you know if the whole trial is now closed or only the Ottawa location because they've reached maximum participation? Was also being run in Kingston and Montreal. 

The clinical trials database hasn't been updated yet and I wasn't able to find  anything that said it was being closed.

I don't know the answer to that.  I do know that they were taken completely by surprise here when they got the notice that it was closed.  As recently as last week, they were still wondering why it was taking so long to get the results for my tumour, as turnaround had previously been 2 weeks, but they weren't getting any response back. 

@jobo

I'm sorry it didn't work out. I do hope you can still get the results of your tumour sample. Results would be a great help in guiding your journey in the future. Wishing you the best 🤗.