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clinical trials

  • 1.  clinical trials

    Posted 03-23-2025 08:19

    ELAHERE clinical trial for platinum-sensitive Teal Sisters

    I saw this on the clinical trials site and wanted to share with you. There are a lot of locations for this trial…Alberta, BC, Quebec and Ontario.

    Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Ovarian, Fallopian Tube, or Peritoneal Cancer (GLORIOSA)

    https://clinicaltrials.gov/study/NCT05445778?



  • 2.  RE: clinical trials

    Posted 03-24-2025 07:47
    I am new to the group and saw this.
    At Princess Margaret last week we were told this was not yet available in Canada.
    I am there again today and will ask
    Thanks for finding this information
    I will try to find time to set myself up with the group.
    Pat from Terra Cotta
    Sent from my iPad




  • 3.  RE: clinical trials

    Posted 03-24-2025 09:17

    Hi @pat from Terra Cotta. Welcome to the OVdialogue group. The Teal Sisters here are a wealth of information, plus pretty darn good at providing virtual support when needed. When as you said, you have time, please introduce yourself and tell us your story. There's a category called "Introductions" in the drop down list at the top left of this webpage. I found the sharing very helpful when I first joined as some of my experiences resonated with others which helped make it easy to connect with them. If you have any initial questions, comments etc. either about the forum, resources available, or specific to your situation let us know that too. We are here to help each other.

    If you haven't found it yet, there is an amazing Resource Guide you an download and/or order a hard copy from the OVD website. Here's a link:

    https://ovariancanada.org/resources/support-resources

    As an aside I too am treated at PMH. I have a wonderful medical team and have been nothing but impressed with the entire PMH medical community. I hope you will have that same experience too, especially in such a difficult time. Again, welcome. Talk soon. 




  • 4.  RE: clinical trials

    Posted 03-24-2025 09:29

    Hi @pat

    Welcome to OVDialogue. This is a great place to find support and information.

    You are correct…the drug is currently under review for approval for use in Canada as a standard of care drug. However, when there is a clinical trial with a drug, and the clinical trial is available in Canada and you meet trial criteria, you can participate and potentially receive the drug. 

    This clinical trial is for platinum-sensitive OC only. For those of us platinum-resistant, we are anxiously awaiting approval of this drug for use in Canada.




  • 5.  RE: clinical trials

    Posted 03-24-2025 10:12
    I am also platinum resistant so will see today if there is anything to offer.
    Sent from my iPad




  • 6.  RE: clinical trials

    Posted 04-01-2025 14:58

    @pat   Welcome to the group.  Thank you for sharing this information.  I am positive it may help someone at some point in time. When you do have time to introduce yourself to the group, please do so. It would be lovely to hear your story and what brought you here.  In the meantime, you can use Teal Thursdays as a way to connect with the group and tell  us where you are at in the week.  How are you and what has brought you here would be a start. That way you can connect with others going through the same thing as yourself.  Sounds like you have a busy schedule currently that prevents you from connecting with the group. Hopefully that will ease soon and you will find yourself able to connect with us soon.  I will be on the Teal Thursday this week to get us started and see where everyone is at. Hoping you can join us too.  Take care of you! 




  • 7.  RE: clinical trials

    Posted 03-24-2025 09:17

    @GloHo thank you as always for sharing information on clinical trials!!!




  • 8.  RE: clinical trials

    Posted 03-25-2025 08:34
    @4grandchildren yes. I had indigestion problems after chemo.  I went to my GP and he prescribed medication which helped immensely. 



    Sent from my Galaxy






  • 9.  RE: clinical trials

    Posted 03-25-2025 08:19

    @GloHo Thank you for bringing this study to our attention. Its always nice to have a short cut. 

    I have my 6 month scan next month and hope / expect to be platinum sensitive as my CA 125 remains normal. I recently read a paper suggesting that the use of PARP inhibitors has blurred the 6 month definition by delaying progression. Patients who previously would have been deemed resistant are now classified as sensitive. 

    Welcome to the group Pat. I love the Copper Kettle in Tera Cotta.




  • 10.  RE: clinical trials

    Posted 03-25-2025 08:50

    @mcb thanks for sharing this information. To be honest I had not to this point read information on platinum sensitive vs. resistant so appreciate this information. Fingers crossed all is well with your CT scan however the CA125 low levels are always great to have!




  • 11.  RE: clinical trials

    Posted 03-27-2025 07:07

    @mcb

    Good luck on your scan next month 🤞.

    Thanks for sharing this info. Very interesting  and promising.  




  • 12.  RE: clinical trials

    Posted 7 days ago

    Thank you for sharing this.  I too am carboplatain reactive, but my cancer is low grade so I don't qualify for this study.

    I am presently in another study called Personalized Onco Genomic, available in BC i know for sure. I am on a treatment through this study, with a medication that should fight the specific anomaly they found in my cancer by doing a DNA panel of one of my lesions. It looks like this medication is doing something, as shown on my last CT scan.  

    The side effects of the med I am on are challenging, so we adjusted the dose so I can tolerate it  Keeoing my fingers crossed!




  • 13.  RE: clinical trials

    Posted an hour ago

    @Sylviequebecbc  Checking in to see how your treatment is going and your symptoms. Are they being managed or are you having to tweak some things? How have you been feeling being on it? I have my fingers crossed for you.  Like you, I am LGSC. Nothing is available for me so in the meantime it is day to day living. My cancer numbers continue to climb and I monitor symptoms and eating as the issues come up to hopefully avoid partial bowel blockages.  How have you been doing in that department? How is your eating going? 




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