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Good morning Teal Sisters,

I see that word is getting out about Abraxane, an alternative for those who have experienced a severe reaction to Paclitaxel.  After my initial cancer diagnosis mid-2021 I was prescribed 6 cycles of Paclitaxel and Carboplatin.  During my first infusion I had an immediate negative reaction - stage 3 anaphylaxis.  Paclitaxel was stopped and for subsequent chemo cycles I was admitted to hospital for at least one, if not two, overnights for a very slow infusion over 12 hours.  Thankfully there were no further negative experiences, but I worry about the potential damage caused by the extended time period that the drug was being administered.

More recently my Oncologist removed a 10 cm mass on left ovary.  With pathology indicating cancer recurrence, he has recommended me for a further 6 cycles of chemo.  Due to my severe reaction 4 years ago I am "eligible" for Abraxane in place of Paclitaxel.  My first cycle is Wednesday, May 28th.  My fingers are crossed that all goes well, as the infusion period is 30 minutes and can be administered as a day patient.

I have also dusted off the two Ovarian Cancer Canada guides - By Your Side and Still By Your Side.

I am very grateful for everyone in the medical and research community, as well as my supporters near and far.  Together we are making things better for all women who are diagnosed with this disease.

Be strong!

- Wendy

WEMK  What an awful experience you had four years ago.   I had a reaction for the very first one in 2020, but not nearly as severe as yours.  Extra doses of steroids and Benadryl settled it down, the dosage was slowed and I finished that treatment.  The next five went without a problem.

This time, the plan was for the dosage to be slowed and it went fine for the first treatment, but on Thursday, I recognized the first sensation right away and called the nurse.  Abraxane wasn't available in 2020, according to the pharmacist, so this time there is an alternative and I went back on Friday for that.  It actually took 45 minutes for the infusion and, then, an hour for the Carboplatin, which also has to be administered more slowly, since this is my 3rd time taking it.

The after effects seem to be about the same, except that the pre-meds are one steroid and 2 anti-nausea tablets so I wasn't feeling as loopy when I was done Friday afternoon as I get on Benadryl.  I have my 'preventative' collection on my night table -- Tylenol, Tums, Imodium, and the anti-nausea medication prescribed by the pharmacist.  So far, so good.

Good luck with it all, Wendy.  

Good morning Teal Sisters,

I see that word is getting out about Abraxane, an alternative for those who have experienced a severe reaction to Paclitaxel.  After my initial cancer diagnosis mid-2021 I was prescribed 6 cycles of Paclitaxel and Carboplatin.  During my first infusion I had an immediate negative reaction - stage 3 anaphylaxis.  Paclitaxel was stopped and for subsequent chemo cycles I was admitted to hospital for at least one, if not two, overnights for a very slow infusion over 12 hours.  Thankfully there were no further negative experiences, but I worry about the potential damage caused by the extended time period that the drug was being administered.

More recently my Oncologist removed a 10 cm mass on left ovary.  With pathology indicating cancer recurrence, he has recommended me for a further 6 cycles of chemo.  Due to my severe reaction 4 years ago I am "eligible" for Abraxane in place of Paclitaxel.  My first cycle is Wednesday, May 28th.  My fingers are crossed that all goes well, as the infusion period is 30 minutes and can be administered as a day patient.

I have also dusted off the two Ovarian Cancer Canada guides - By Your Side and Still By Your Side.

I am very grateful for everyone in the medical and research community, as well as my supporters near and far.  Together we are making things better for all women who are diagnosed with this disease.

Be strong!

- Wendy

Good morning Teal Sisters,

I see that word is getting out about Abraxane, an alternative for those who have experienced a severe reaction to Paclitaxel.  After my initial cancer diagnosis mid-2021 I was prescribed 6 cycles of Paclitaxel and Carboplatin.  During my first infusion I had an immediate negative reaction - stage 3 anaphylaxis.  Paclitaxel was stopped and for subsequent chemo cycles I was admitted to hospital for at least one, if not two, overnights for a very slow infusion over 12 hours.  Thankfully there were no further negative experiences, but I worry about the potential damage caused by the extended time period that the drug was being administered.

More recently my Oncologist removed a 10 cm mass on left ovary.  With pathology indicating cancer recurrence, he has recommended me for a further 6 cycles of chemo.  Due to my severe reaction 4 years ago I am "eligible" for Abraxane in place of Paclitaxel.  My first cycle is Wednesday, May 28th.  My fingers are crossed that all goes well, as the infusion period is 30 minutes and can be administered as a day patient.

I have also dusted off the two Ovarian Cancer Canada guides - By Your Side and Still By Your Side.

I am very grateful for everyone in the medical and research community, as well as my supporters near and far.  Together we are making things better for all women who are diagnosed with this disease.

Be strong!

- Wendy

Good morning Teal Sisters,

I see that word is getting out about Abraxane, an alternative for those who have experienced a severe reaction to Paclitaxel.  After my initial cancer diagnosis mid-2021 I was prescribed 6 cycles of Paclitaxel and Carboplatin.  During my first infusion I had an immediate negative reaction - stage 3 anaphylaxis.  Paclitaxel was stopped and for subsequent chemo cycles I was admitted to hospital for at least one, if not two, overnights for a very slow infusion over 12 hours.  Thankfully there were no further negative experiences, but I worry about the potential damage caused by the extended time period that the drug was being administered.

More recently my Oncologist removed a 10 cm mass on left ovary.  With pathology indicating cancer recurrence, he has recommended me for a further 6 cycles of chemo.  Due to my severe reaction 4 years ago I am "eligible" for Abraxane in place of Paclitaxel.  My first cycle is Wednesday, May 28th.  My fingers are crossed that all goes well, as the infusion period is 30 minutes and can be administered as a day patient.

I have also dusted off the two Ovarian Cancer Canada guides - By Your Side and Still By Your Side.

I am very grateful for everyone in the medical and research community, as well as my supporters near and far.  Together we are making things better for all women who are diagnosed with this disease.

Be strong!

- Wendy

Good morning Teal Sisters,

I see that word is getting out about Abraxane, an alternative for those who have experienced a severe reaction to Paclitaxel.  After my initial cancer diagnosis mid-2021 I was prescribed 6 cycles of Paclitaxel and Carboplatin.  During my first infusion I had an immediate negative reaction - stage 3 anaphylaxis.  Paclitaxel was stopped and for subsequent chemo cycles I was admitted to hospital for at least one, if not two, overnights for a very slow infusion over 12 hours.  Thankfully there were no further negative experiences, but I worry about the potential damage caused by the extended time period that the drug was being administered.

More recently my Oncologist removed a 10 cm mass on left ovary.  With pathology indicating cancer recurrence, he has recommended me for a further 6 cycles of chemo.  Due to my severe reaction 4 years ago I am "eligible" for Abraxane in place of Paclitaxel.  My first cycle is Wednesday, May 28th.  My fingers are crossed that all goes well, as the infusion period is 30 minutes and can be administered as a day patient.

I have also dusted off the two Ovarian Cancer Canada guides - By Your Side and Still By Your Side.

I am very grateful for everyone in the medical and research community, as well as my supporters near and far.  Together we are making things better for all women who are diagnosed with this disease.

Be strong!

- Wendy

Good morning Teal Sisters,

I see that word is getting out about Abraxane, an alternative for those who have experienced a severe reaction to Paclitaxel.  After my initial cancer diagnosis mid-2021 I was prescribed 6 cycles of Paclitaxel and Carboplatin.  During my first infusion I had an immediate negative reaction - stage 3 anaphylaxis.  Paclitaxel was stopped and for subsequent chemo cycles I was admitted to hospital for at least one, if not two, overnights for a very slow infusion over 12 hours.  Thankfully there were no further negative experiences, but I worry about the potential damage caused by the extended time period that the drug was being administered.

More recently my Oncologist removed a 10 cm mass on left ovary.  With pathology indicating cancer recurrence, he has recommended me for a further 6 cycles of chemo.  Due to my severe reaction 4 years ago I am "eligible" for Abraxane in place of Paclitaxel.  My first cycle is Wednesday, May 28th.  My fingers are crossed that all goes well, as the infusion period is 30 minutes and can be administered as a day patient.

I have also dusted off the two Ovarian Cancer Canada guides - By Your Side and Still By Your Side.

I am very grateful for everyone in the medical and research community, as well as my supporters near and far.  Together we are making things better for all women who are diagnosed with this disease.

Be strong!

- Wendy

Hi Wendy and friends,

I had a similar experience as you and others with Paclitaxel, and was switched to Abraxane (with a lot of fighting for it) for the remainder of my treatments. As Lisa mentioned, it was a shorter infusion, but again, I had the same side effects as the standard Paclitaxel. 

I feel strongly that we need to advocate for the use of Abraxane for folks. There are way TOO MANY stories of people having severe reactions, it needs to stop. It is so traumatic and scary, we shouldn't be put through more stress than we are already experiencing. 

With kindness,

Tiffany

Good morning Teal Sisters,

I see that word is getting out about Abraxane, an alternative for those who have experienced a severe reaction to Paclitaxel.  After my initial cancer diagnosis mid-2021 I was prescribed 6 cycles of Paclitaxel and Carboplatin.  During my first infusion I had an immediate negative reaction - stage 3 anaphylaxis.  Paclitaxel was stopped and for subsequent chemo cycles I was admitted to hospital for at least one, if not two, overnights for a very slow infusion over 12 hours.  Thankfully there were no further negative experiences, but I worry about the potential damage caused by the extended time period that the drug was being administered.

More recently my Oncologist removed a 10 cm mass on left ovary.  With pathology indicating cancer recurrence, he has recommended me for a further 6 cycles of chemo.  Due to my severe reaction 4 years ago I am "eligible" for Abraxane in place of Paclitaxel.  My first cycle is Wednesday, May 28th.  My fingers are crossed that all goes well, as the infusion period is 30 minutes and can be administered as a day patient.

I have also dusted off the two Ovarian Cancer Canada guides - By Your Side and Still By Your Side.

I am very grateful for everyone in the medical and research community, as well as my supporters near and far.  Together we are making things better for all women who are diagnosed with this disease.

Be strong!

- Wendy

Hi Wendy and friends,

I had a similar experience as you and others with Paclitaxel, and was switched to Abraxane (with a lot of fighting for it) for the remainder of my treatments. As Lisa mentioned, it was a shorter infusion, but again, I had the same side effects as the standard Paclitaxel. 

I feel strongly that we need to advocate for the use of Abraxane for folks. There are way TOO MANY stories of people having severe reactions, it needs to stop. It is so traumatic and scary, we shouldn't be put through more stress than we are already experiencing. 

With kindness,

Tiffany

Good morning Teal Sisters,

I see that word is getting out about Abraxane, an alternative for those who have experienced a severe reaction to Paclitaxel.  After my initial cancer diagnosis mid-2021 I was prescribed 6 cycles of Paclitaxel and Carboplatin.  During my first infusion I had an immediate negative reaction - stage 3 anaphylaxis.  Paclitaxel was stopped and for subsequent chemo cycles I was admitted to hospital for at least one, if not two, overnights for a very slow infusion over 12 hours.  Thankfully there were no further negative experiences, but I worry about the potential damage caused by the extended time period that the drug was being administered.

More recently my Oncologist removed a 10 cm mass on left ovary.  With pathology indicating cancer recurrence, he has recommended me for a further 6 cycles of chemo.  Due to my severe reaction 4 years ago I am "eligible" for Abraxane in place of Paclitaxel.  My first cycle is Wednesday, May 28th.  My fingers are crossed that all goes well, as the infusion period is 30 minutes and can be administered as a day patient.

I have also dusted off the two Ovarian Cancer Canada guides - By Your Side and Still By Your Side.

I am very grateful for everyone in the medical and research community, as well as my supporters near and far.  Together we are making things better for all women who are diagnosed with this disease.

Be strong!

- Wendy

Good morning Teal Sisters,

I see that word is getting out about Abraxane, an alternative for those who have experienced a severe reaction to Paclitaxel.  After my initial cancer diagnosis mid-2021 I was prescribed 6 cycles of Paclitaxel and Carboplatin.  During my first infusion I had an immediate negative reaction - stage 3 anaphylaxis.  Paclitaxel was stopped and for subsequent chemo cycles I was admitted to hospital for at least one, if not two, overnights for a very slow infusion over 12 hours.  Thankfully there were no further negative experiences, but I worry about the potential damage caused by the extended time period that the drug was being administered.

More recently my Oncologist removed a 10 cm mass on left ovary.  With pathology indicating cancer recurrence, he has recommended me for a further 6 cycles of chemo.  Due to my severe reaction 4 years ago I am "eligible" for Abraxane in place of Paclitaxel.  My first cycle is Wednesday, May 28th.  My fingers are crossed that all goes well, as the infusion period is 30 minutes and can be administered as a day patient.

I have also dusted off the two Ovarian Cancer Canada guides - By Your Side and Still By Your Side.

I am very grateful for everyone in the medical and research community, as well as my supporters near and far.  Together we are making things better for all women who are diagnosed with this disease.

Be strong!

- Wendy

Hi Wendy,

I was switched to Nab-Paclitaxel after having a serious reaction to Paclitaxel and my body was able to tolerate the infusions, but I did continue to have reactions even to the Nab-Paclitaxel, despite pre-medication with high dose steroids and antihistamines starting the day prior to infusions. 

The reactions were less intense with the Nab-Paclitaxel but were still unpleasant and unnerving.

I thought I would share my experience in case you did have a mild reaction to the Arbraxane, to let you know that it might happen, and that it doesn't necessarily mean that you won't be able to get through the treatment.

Best of luck with everything, I'm rooting for you!

Warmly, 

Petra

Good morning Teal Sisters,

I see that word is getting out about Abraxane, an alternative for those who have experienced a severe reaction to Paclitaxel.  After my initial cancer diagnosis mid-2021 I was prescribed 6 cycles of Paclitaxel and Carboplatin.  During my first infusion I had an immediate negative reaction - stage 3 anaphylaxis.  Paclitaxel was stopped and for subsequent chemo cycles I was admitted to hospital for at least one, if not two, overnights for a very slow infusion over 12 hours.  Thankfully there were no further negative experiences, but I worry about the potential damage caused by the extended time period that the drug was being administered.

More recently my Oncologist removed a 10 cm mass on left ovary.  With pathology indicating cancer recurrence, he has recommended me for a further 6 cycles of chemo.  Due to my severe reaction 4 years ago I am "eligible" for Abraxane in place of Paclitaxel.  My first cycle is Wednesday, May 28th.  My fingers are crossed that all goes well, as the infusion period is 30 minutes and can be administered as a day patient.

I have also dusted off the two Ovarian Cancer Canada guides - By Your Side and Still By Your Side.

I am very grateful for everyone in the medical and research community, as well as my supporters near and far.  Together we are making things better for all women who are diagnosed with this disease.

Be strong!

- Wendy

Thanks for sharing your experience Petra. I appreciate your support. So far (2 cycles) I have had absolutely no ill founded reaction to Abraxane, with a steroid and an antihistamine 45 minutes before infusion starts. 

I am grateful as there are so many other negative side effects from the treatment. 

Best regards, Wendy

Hi Wendy,

I was switched to Nab-Paclitaxel after having a serious reaction to Paclitaxel and my body was able to tolerate the infusions, but I did continue to have reactions even to the Nab-Paclitaxel, despite pre-medication with high dose steroids and antihistamines starting the day prior to infusions. 

The reactions were less intense with the Nab-Paclitaxel but were still unpleasant and unnerving.

I thought I would share my experience in case you did have a mild reaction to the Arbraxane, to let you know that it might happen, and that it doesn't necessarily mean that you won't be able to get through the treatment.

Best of luck with everything, I'm rooting for you!

Warmly, 

Petra

Good morning Teal Sisters,

I see that word is getting out about Abraxane, an alternative for those who have experienced a severe reaction to Paclitaxel.  After my initial cancer diagnosis mid-2021 I was prescribed 6 cycles of Paclitaxel and Carboplatin.  During my first infusion I had an immediate negative reaction - stage 3 anaphylaxis.  Paclitaxel was stopped and for subsequent chemo cycles I was admitted to hospital for at least one, if not two, overnights for a very slow infusion over 12 hours.  Thankfully there were no further negative experiences, but I worry about the potential damage caused by the extended time period that the drug was being administered.

More recently my Oncologist removed a 10 cm mass on left ovary.  With pathology indicating cancer recurrence, he has recommended me for a further 6 cycles of chemo.  Due to my severe reaction 4 years ago I am "eligible" for Abraxane in place of Paclitaxel.  My first cycle is Wednesday, May 28th.  My fingers are crossed that all goes well, as the infusion period is 30 minutes and can be administered as a day patient.

I have also dusted off the two Ovarian Cancer Canada guides - By Your Side and Still By Your Side.

I am very grateful for everyone in the medical and research community, as well as my supporters near and far.  Together we are making things better for all women who are diagnosed with this disease.

Be strong!

- Wendy