Hello all and thanks for your attention and responses,
I was diagnosed with stage 4B high grade serous cell carcinoma in November 2018. I have been through total surgery: hysterectomy, appendectomy, and removal of omentum ; 2 rounds of chemo and am now facing the decision about whether to proceed with another round of chemo which is projected to have a 30% success rate.
I want to hear about others experiences with paclitaxel spread over 3 weeks. I understand everyone is different so I cannot expect my experience to mimic others so please chime in and be one of a few or hopefully several responses. I am presently living alone independently, able to go for 90 minute walks on level surfaces and have pretty good quality of life. I am afraid that I will spend two months in treatment, the treatment will be ineffective and the end of my life will have be in illness. Remembering Popeye's friend Wimpy - I'd rather have a hamburger today.
First round was carboplatin and paclitaxel - once every 3 weeks x 6 cycles
It was tough, couch bound for 5-7 days after each treatment, some vomiting, progressive increase in foot neuropathy resulting in no paclitaxel, only carbo the last treatment due to neuropathy, went 12 months before new growth on CT. (neuropathy significantly reduced 3 months after treatment ended-yeah!)
Second round was carboplatin and gemcitabine, 21 day cycle - C&G day 1, G only day 8, then a week off. Several times neutrophils and platelets too low so treatment was delayed a week. Felt unpredictably lousy and well through the entire 21 day cycle which kept me close to home last summer, no walks or day trips. On reflection I was like the frog in a pot of boiling water. Wouldn't have survived if I had jumped into the boiling water but because it was being heated gradually I stayed in the pot. After 6 cycles drugs continued to work so was recommended to have 3 more cycles however when blood counts didn't recover after 2 weeks and I am palliative "drug holiday" was recommended.
After 3 months CT shows changes and CA125 is elevated.
Now I am told that Carboplatin is no longer effective and I am offered the same dose of paclitaxel but over 3 weeks then a week off.
I am in BC.
Thanks again for your attention,