Hi everyone, I'm hoping to gather some info on Genetic or Genome Testing. Here is my updated situation. I was diagnosed Stage 3C - High Grade Serous ovarian cancer - involving both ovaries. The first 3 roundsof Carbo/Paclatax did nothing, the surgery was postponed, then put on Doxil./Carbo for three rounds, which resulting in the cancer is now stable but also found out it now involves my liver and lungs. Now decision for three more rounds, then CT to see if the Doxil has started to reduce the size of the turmors/cancer. I have an appoint with BC Cancer Agency for Hereditary Cancer assessment. I have a lot of cancer in my family so I assume it is a hereditary issue. I am confused about the difference between Genetic and Genome testing. If my cancer is a result of mutated cell (whether familial Brca 1 or Braca2) is there somewhere I can get testing done so I can hopefully be provided the specific mutation and also hopefully get Targeted treatment. I live in British Columbia and have no problem providing fund for private testing if necessary.
Sorry if I come across a little confused but to be honest I am (Chemo yesterday and notified of lung and liver involvement 2 days ago)
I look forward to any thoughts you ladies might have.
I hope you have been managing well with the treatments.
The comment I can share on this topic is about the POG study in BC.
I watched the documentary on it and it was very interesting.
There are many topics here on the site and perhaps you may find some more info on the BRCA status details and more by entering the topic on the search bar at the top right.
I'll also private message you.
It is likely just coincidental that both of you contracted the same disease, but suggest you or she revert to your respective oncologists about further genetic testing. The "coincidence' certainly warrants that discussion.
If you and/or your daughter are registered for the virtual Symposium starting tonite, there is a session on genetics at around 1pm EST tomorrow that might be helpful. And if you haven't registered, I believe there is still time to do so and receive the sign in link. As both of you being new to this disease there are several sessions that you might find extremely helpful as you navigate your journeys. Go to ovariancanada.org/fallsymposium to view the full agenda and register.
Finally, if there is anything more we can do to support the two of you please do reach out. Our community is 900 strong from all across the country and all with their own stories and experiences to share. You are not alone.
If a person was interested in a more extensive analysis, private facilities will test for up to 400 genomic mutations. A report is generated that co-relates the genomic results with currently available effective treatment options and open drug trials. This testing procedure is something done by a patient outside of the cancer center. Foundation One located in Mississauga Ontario offers this service.
Testing is quite simple. Either a portion of the tissue taken during surgery is sent off for analysis or you provide a quick blood sample for assessment. The former seems to be the approach taken these days. I do urge you to discuss this with your cancer care team before you dismiss the opportunity.
Wishing you a very successful surgery.